How to Give a B12 Injection: Step By Step Instructions B12 vitamin Store A Manual for you all: What are B12 injections? Where to give B12 injections shots? How to give B12 injections? Best Vitamin B12 Injection Sites: Where to Inject B12 PA Relief Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches