The antioxidant glutathione ScienceDirect Glutathione is a natural antioxidant your body makes, and it can influence melanin production which is why its sometimes marketed for skin brightening., Oral supplements are mostly broken down in Glutathione vs Astaxanthin BOTH are powerful antioxidants but they work differently Think of them as elite defenders against oxidative stress (cell damage). Glutathione = the MASTER antioxidant inside your body Why is Glutathione the Key to Gut Health?